Digitalis ved hjertesvikt – fortsatt et aktuelt behandlingsprinsipp?

Cord Arend Manhenke; Kenneth Dickstein

Digitalis ved hjertesvikt – fortsatt et aktuelt behandlingsprinsipp?

Legemidler i praksis

Cord Arend Manhenke, Kenneth Dickstein Om forfatterne

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Cord Arend Manhenke

Email: cord@online.no

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Kenneth Dickstein

Kardiologisk seksjon

Sentralsjukehuset i Rogaland

Postboks 8100

4003 Stavanger

Artikkel

Litteratur

Gjesdal K. Digitalis ved atrieflimmer. Tidsskr Nor Lægeforen 1996; 116: 973 – 5.

Newton GE, Tang JH, Schofield AM, Baines AD, Floras JS, Parker JD. Digoxin reduces sympathetic nerve activity in severe congestive heart failure. J Am Cardiol 1996; 28: 155 – 61.

Packer M, Gheorghiade M, Young JB, Smith LK, Constantini PJ, Adams KF et al., for the RADIANCE study. Withdrawal of digoxin from patients with chronic heart failure treated with angiotensin-converting enzyme inhibitors. N Engl J Med 1993; 329: 1 – 7.

Uretsky BF, Young JB, Shahidi FE, Yellen LG, Harrison MC, Jolly MK et al. Randomized study assessing the effect of digoxin withdrawal in patients with mild to moderate chronic congestive heart failure: results of the PROVED trial. J Am Coll Cardiol 1993; 22: 955 – 62.

Digitalis Investigation Group. The effect of digoxin on mortality and morbidity in patients with heart failure. N Engl J Med 1997; 336: 525 – 33.

Gheorghiade M, Hall VB, Jacobsen G, Alam M, Rosman H, Goldstein S. Effects of increasing maintenance dose of digoxin on left ventricular function and neurohormones in patients with chronic heart failure treated with diuretics and angiotensin-converting enzyme inhibitors. Circulation 1995; 92: 1801 – 7.

Yusuf S, Garg R, Held P, Gorlin R. Need for a large randomized trial to evaluate the effect of digitalis on morbidity and mortality in congestive heart failure. Am J Cardiol 1992; 69: 64G – 70G.

Gheorghiade M, Pitt B, Digitalis Investigation Group (DIG) trial: a stimulus for further research. Am Heart J 1997; 134: 3 – 12.

Pitt B, Zannad F, Remme WJ, Cody R, Castaigne A, Perez A et al. The effect of Spironolactone on morbidity and mortality in patients with severe heart failure. N Engl J Med 1999; 341: 709 – 17.

MERIT HF Study Group. Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomized Intervention Trial in Congestive Heart Failure (MERIT-HF). Lancet 1999; 353: 2001 – 7.

CIBIS-II Investigators and Committees. The Cardiac Insufficiency Bisoprolol Study II (CIBIS-II): a randomized trial. Lancet 1999; 353: 9 – 13.

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Publisert: 20. januar 2001

Utgave 02, 20. januar 2001

Tidsskr Nor Lægeforen 2001;

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Digitalis ved hjertesvikt – fortsatt et aktuelt behandlingsprinsipp?

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